Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in living cells.
نویسندگان
چکیده
Biophysical understanding of cellular glucose uptake led us to the development of an image-based high-throughput screening system by using a fluorescent glucose bioprobe, GB2. The accuracy, robustness, and practicality of our image-based HTS system were demonstrated through the pilot screening and the subsequent in vitro confirmation.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 45 شماره
صفحات -
تاریخ انتشار 2013